Hien Nguyen, Ph.D.

Hien Nguyen, Ph.D.
Assistant Professor, School of Science, Engineering, and Technology
Office Phone
777 West Harrisburg Pike
Middletown, PA 17057

I am a bioinformatician. My work has been on developing mathematical and statistical models to capture the dynamics of biological processes, particularly in cancer. My recent research interests include: (i) association of genome, transcriptome, and proteome in tumors, (ii) recombination in mitochondrial genome, (iii) directional inference in biological interactions, and (iv) mathematical modeling of biological pattern formation.

Research Interests

Cancer informatics


Systems biology

Pattern formation


H. Nguyen, S. Tilton, C. Kemp, and M. Song. (2017) Non-monotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose. Cancer Informatics, vol. 16, pages 1-13. PubMed ID: 29162974. URL: http://journals.sagepub.com/doi/full/10.1177/1176935117740132

T. Cotton, H. Nguyen, J. I. Said, Z. Ouyang, J. Zhang, and M. Song. (2015) Discerning mechanistically rewired biological pathways by cumulative interaction heterogeneity statistics. Scientific Reports, vol. 5, article 9634. PubMed ID: 25921728. URL: https://www.nature.com/articles/srep09634

H. Nguyen and M. Song. (2012) Integrated cellular and gene interaction modeling of pattern formation. International Journal of Computational Biology and Drug Design, vol. 4, no. 4, pages 361-372. PubMed ID: 22199036. URL: http://www.inderscience.com/info/inarticle.php?artid=44444

H. Nguyen and M. Song. (2011) Integrated cellular and gene interaction model for cell migration in embryonic development. In Proceedings of IEEE International Conference on Bioinformatics and Biomedicine, pages 229-233.


New Mexico State University, Ph.D. in Computer Science