Hien Nguyen, Ph.D.

Hien Nguyen, Ph.D.
Assistant Professor of Computer Science, School of Science, Engineering, and Technology
Olmsted Building, W255B
W255B OLMSTED BLDG
PENN STATE HBG
MIDDLETOWN, PA 17057

I am a bioinformatician. My work has been on developing mathematical and statistical models to capture the dynamics of biological processes, particularly in cancer. My recent research interests include: (i) association of genome, transcriptome, and proteome in tumors, (ii) recombination in mitochondrial genome, (iii) directional inference in biological interactions, and (iv) mathematical modeling of biological pattern formation.

  • Cancer informatics
  • Biostatistics
  • Systems biology
  • Pattern formation

H. Nguyen, S. Tilton, C. Kemp, and M. Song. (2017) Non-monotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose. Cancer Informatics, vol. 16, pages 1-13. PubMed ID: 29162974. 

T. Cotton, H. Nguyen, J. I. Said, Z. Ouyang, J. Zhang, and M. Song. (2015) Discerning mechanistically rewired biological pathways by cumulative interaction heterogeneity statistics. Scientific Reports, vol. 5, article 9634. PubMed ID: 25921728. 

H. Nguyen and M. Song. (2012) Integrated cellular and gene interaction modeling of pattern formation. International Journal of Computational Biology and Drug Design, vol. 4, no. 4, pages 361-372. PubMed ID: 22199036. 

H. Nguyen and M. Song. (2011) Integrated cellular and gene interaction model for cell migration in embryonic development. In Proceedings of IEEE International Conference on Bioinformatics and Biomedicine, pages 229-233.

New Mexico State University, Ph.D. in Computer Science