Middletown, PA 17057
Biography
Prof. Purnima Neogi is a faculty member at Penn State University, specializing in biotechnology, nanotechnology, and bioengineering. Her research spans multiple disciplines, focusing on plant tissue culture, bio-nanotechnology, and plant biotechnology, particularly in plant oil metabolism and the application of nanoparticles in both plant and animal systems. She holds a Ph.D. and M. Phil in Life Sciences and Biotechnology from Devi Ahilya University, where she developed a passion for applying biotechnology to plant systems. Throughout her career, she has collaborated with scientists internationally, bridging the gap between life sciences and engineering.
In addition to her research, Prof. Neogi is dedicated to teaching and mentoring students. She strives to create an interactive learning environment that fosters curiosity, critical thinking, and collaboration. At Penn State, she teaches undergraduate courses in biology, ecology, and biotechnology. Her classes are known for their rigor, real-world applications, and relevance, and she integrates cutting-edge research into her lessons, ensuring that students gain a comprehensive understanding of both theoretical and practical aspects of these fields. Her courses also emphasize emerging technologies' ethical and societal implications, preparing students to think critically about how their work can address global challenges.
Prof. Neogi’s research at the University of North Texas focused on the development of nanoparticles for non-invasive imaging and therapeutic applications, including ZnO nanoparticles, which are known for their unique second-harmonic generation (SHG) properties. These nanoparticles have shown promise for use in plant and animal cell tracking, as well as in medical applications like photodynamic therapy for targeted treatments, including cancer therapy.
In agricultural biotechnology, Prof. Neogi has contributed significantly to improving crop productivity through genetic engineering. Her research on cotton aims to understand better the mechanisms of oil accumulation in transgenic cotton seeds to enhance oil and fiber production for industrial applications. This work also provides insights into plant lipid metabolism, with broader implications for sustainable agricultural practices.
Prof. Neogi’s interdisciplinary research approach has led to successful collaborations with academic institutions and industry partners in the U.S., Japan, and India. Through these collaborations, she continues to advance the fields of biotechnology and nanotechnology, making important contributions to agriculture, healthcare, and environmental sustainability.
Research Interests
- Plant tissue culture and genetics
- Somatic embryogenesis and secondary metabolite production through tissue
culture - Engineering fatty acid metabolism in Cotton.
- Nano-Biophotonics using plant and cancer cells.
Publications
D Reyes, H Heo, ÁM Martínez-Argüello, Y Fujita, PB Neogi, A Neogi, IEEE Open Journal of Ultrasonics, Ferroelectrics, and Frequency Control,” Underwater analyte sensing using a phononic crystal waveguide-based interferometric acoustic spectrometer, vol. 4, pp. 216-226, 2024”.
Sween B, Purnima Neogi, Ben Urban, Yasuhisa Fujita, Zhibing Hu, Arup Neogi; ZnO Nanoparticles in Hydrogel Polymer Network for Bio-Imaging. Glob J Nano. 2017; 1(5): 555572.
Ben E. Urban, Purnima B. Neogi, Surendra Kumar Rajpurohit, Pudur Jagadeeshwaran, Yasuhisa Fujita, Arup Neogi, Optimization of Nonlinear Optical Properties of ZnO nanoparticles for Live Cell Imaging, IEEE J. Spec. Topic in Quantum Electron, 2012, DOI: 10.1109/JSTQE.2012.2184793.
Patrick J. Horn, Andrew R. Korte, Purnima B. Neogi, Ebony Love, Johannes Fuchs, Kerstin, Strupat, Ljudmilla Borisjuk, Vladimir Shulaev, Young-Jin Lee, Kent D. Chapman, Spatial mapping of lipids at cellular resolution in embryos of Gossypium hirsutum, L 2012, Plant Cell 2012, vol. 24 no. 2 622-636.
Ben E. Urban, Purnima B. Neogi, Sween J. Butler, Yasuhisa Fujita, Arup Neogi, Second harmonic imaging of plants tissues and cell implosion using two-photon process in ZnO nanoparticles, J. Biophotonics, 4, 1-9 (2011) DOI 10.1002/jbio.201100076
Patrick J. Horn, Purnima Neogi, Xenia Tombokan, Supriyo Ghosh and B. Todd Campbell, Simultaneous Quantification of Oil and Protein in Cottonseed by Low-Field Time-Domain Nuclear Magnetic Resonance; 2011; 88, Journal of the American Oil Chemists' Society.
Kyung-Min Lee, Arup Neogi, Purnima Basu Neogi, Minjung Kim, Bongsoo Kim,c Rafal Luchowski, Zygmunt Gryczynski, Nils Calander, and Tae-Youl Choi, Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging, (2011), Journal of Biomedical Optics 16, 056008.
Daiyuan Zhang, Irma L. Pirtle, Stacy J. Park, Mongkol Nampaisansuk, Purnima Neogi, Sylvia W. Wanjie, Robert M. Pirtle and Kent D. Chapman Identification and expression of a new delta-12 fatty acid desaturase (FAD2-4) gene in upland cotton and its functional expression in yeast and Arabidopsis thaliana plants, Plant Physiology and Biochemistry, 2009: 47(6) 462-471.
Kent D. Chapman, Purnima B. Neogi, Kater D. Hake, Agnes A. Stawska, Thomas R. Speed, Matthew Q. Cotter, David C. Garrett, Thomas Kerby, Charlene D. Richardson, Brian G. Ayre, Supriyo Ghosh, and Anthony J. Kinney. Reduced Oil Accumulation in Cottonseeds Transformed with a Brassica Nonfunctional Allele of a Delta-12 Fatty Acid Desaturase (FAD2) Crop Sci.2008; 48: 1470-1481. FAD2-2B cDNAs sequence deposited in GenBank (accession number EU363790) 2009
Laurent Coque, Purnima Neogi, Catalina Pislariu, Kimberly A. Wilson, Christina Catalano, Madhavi Avadhani, D. Janine Sherrier, and Rebecca Dickstein. Transcription of ENOD8 in Medicago truncatula Nodules Directs ENOD8 Esterase to Developing and Mature Symbiosomes. MPMI 21:4 2008: 404-410
H. Liddar, J. Li, A. Neogi, P.B. Neogi, A. Sarkar, S. Cho, H. Morkoc, “Self-assembled deoxyguanosine based molecular electronic device on GaN, substrates, Appl. Phys. Lett, 92,13309, (2008)
P. B. Neogi, A. A. Stawska, K.D. Hake, T. R. Speed, M. Q. Cotter, D. C. Garrett, T. Kerby, A. J. Kinney, K.D. Chapman, “Reduced oil and protein accumulation in cotton seeds transformed with a Brassica non-functional allele of a delta-12 desaturase (FAD2),”. American society of plant biologists, Boston,2006.
P.B. Neogi, L.Coque, R. Dickstein,” The Medicago ENOD8 nodulin gene encodes an esterase, localizing in specific tissues of root nodules,”American society of plant biologists, Boston, 2006.
P. B. Neogi, M. Nakashima, S. Toki, H. Ichikawa, “Development of an efficient morphological marker using ipt (isopentenyl transferase) gene in rice”, (Communicated ’08).
J. Li, A. Sarkar, P. Neogi, H. Morkoc, A. Neogi, “Design of hybrid GaN photonic bandgap structures embe ded with olegonucleotide based molecular wires for UV-Visible regime” Extended Advanced International Meeting on Optical Materials, Tucson (2005).
M. Nakashima, P. B. Neogi, H. Nakamura, N. Mimida, A. Tagiri, H.Onodera, S. Toki, J. Hashimoto, H. Ichikawa, “A D-type cyclin from rice potentially involved in leaf formation, ”46th Annual Meeting of the Japanese Society of Plant Physiologists, Niigata, Japan (2005),
A. Neogi, J. Li, A. Sarkar, P.B. Neogi, and H. Morkoc, “Self-assembled modified deoxyguanosines conjugated to GaN quantum dots for biophotonic applications”, Electronic Letters, 40, 1605 (2004).
A. Neogi, P.B. Neogi, and H. Morkoc, “Radiative Decay Engineering in GaN quantum dots for biomedical a plication”, Applied Physics Society, Austin 2003.
M. Nakashima, P.B. Neogi, E. Okano, J. Hashimoto, T. Sasaki, and H. Ichikawa, “Oryza sativa (japonica cu tivar- group) OsCycD mRNA for cyclin, complete cds., DDBJ/EMBL/Gene Bank nucleotide sequence under the accession no. AB080248 (2002)
P.B. Neogi, Y. Nishizawa, K. Ono, H. Wabiko, M. Ugaki, S. Toki, H. Ichikawa, “Morphological and Conditional Negative Selection Markers for Efficient Gene Targeting in Rice”, Proc. IX Int. Conference on Plant and Genome, pg. 99, (2001)
P.B. Neogi, S. Endo, H. Ebinuma, H. Wabiko, and H. Ichikawa, “Agrobacterium tumefaciens plasmid pTiAKE10 iaaM ,ipt, 6b genes for tryptophan monooxygenase” partial and complete cds DDBJ/EMBL/Gene Bank nucleotide sequence under the accession no. AB032122 (1999)
P.B. Neogi and J. Onodera, “Direct somatic embryogenesis, regeneration and pigment accumulation in Carthamus tinctorius L.”, Proc. American Asso. for Advancement of Sciences, Anaheim, California (1999).
H. Tanaka, P.B. Neogi, N. Naoko, Y, Tabei, Y. Ban, T. Kayano and F. Takaiwa, “Regeneration Conditions for Soybean (Glycin max(L.) Merr.)”, Extended Abstract Ann. Meet, of Japanese Soc. of Breeding (1998).
P. Basu, S. Chand, "Tropane alkaloids from callus cultures, differentiated roots and shoots of Hyoscyamus muticus L." J Plant Biochem. Biot 7 (1): 39-42 (1998).
S. Chand, P. Basu, "Embryogenesis and plant regeneration from callus cultures derived from unpollinated ovaries of Hyoscyamus muticus L.", Plant Cell Rep. 17 (4): 302-305 FEB 1998
P. Basu, S. Chand, "Anthocyanin accumulation in Hyoscyamus muticus L tissue cultures," J. Biotech. 52 (2): 151-159 DEC 10 1996; Erratum:, J Biotech. 58 (3): 209-209 DEC 3 1997.
Education
- Ph.D., Life Science (Plant Tissue Culture and Genetics: Devi Ahilya University, India)
- M.Phil., Life Science (Devi Ahilya University, India)
- M.S., Genetics (Bhopal University, Bhopal, India